Suburban America gone haywire. In the midst of a serial abductor/killer's rampage, a beautiful young teen, Riley Lawson, goes missing. When her desperate parents, Will and Kate, are contacted by her kidnapper, an insufferable FBI Special Agent takes charge of the case.But, from deep within the psychopathic subterranean world created by Otis, Riley turns the tables on her tormentor, manages to escape and to contact her parents. And, fed up with the tragi-comic inability of the FBI to find their girl, Will, Kate, and Riley's brother, Reed decide to take matters - and justice - into their own hands.

On the day after his fortieth birthday, the family man and computer analyst George Grieves goes to the Mt. Abaddon Hospital for a routine procedure of colonoscopy with Dr. Sharazi. Along his birthday party, his friends and family tell many cases of medical errors, and George is worried about. After the surgery, George finds that his surgery had complications because of a homonymous patient, and he had received a thoracoscopic sympathectomy instead. While interned, George discloses bizarre and dark secrets about the East Wing of the hospital while his wife and family have to take a decision about his fate.